Outcomes of MDS/MPN
Outcomes for MDS/MPNs vary from person to person. Your consultant is the best person to advise you on what they expect for you.
Overall outcomes of MDS/MPNs
Outcomes for people with MDS/MPNs vary from person to person. They depend on many factors, such as:
- The exact type of MDS/MPN you have
- The genetic changes in your cancer cells
- Your age
- Your blood test results
Here, we cover overall survival figures. These are averages. They cannot tell you what will happen to you.
Overall survival figures are based on what happened to groups of people with a similar diagnosis in the past. They use data collected over many years, when people may not have received treatments that are available now.
For MDS/MPNs, outcomes vary depending on your exact diagnosis.
MDS/MPN with neutrophilia
People with MDS/MPN with neutrophilia live for an average of 12 to 24 months. Some people do not live as long as this. Others live longer.
MDS/MPN with SF3B1 mutation and thrombocytosis
People with MDS/MPN with SF3B1 mutation and thrombocytosis live for an average of 69 to 79 months. Some people do not live as long as this. Others live longer.
MDS/MPN not otherwise specified
People with MDS/MPN not otherwise specified live for an average of 12 to 28 months. Some people do not live as long as this. Others live longer. This category includes any type of MDS/MPN that does not fit into other categories. This means outcomes are very variable and it is even harder to draw conclusions.
If you want to know as much as possible about your outlook, talk to your haematology team. They will be able to take into consideration everything they know about you, your MDS/MPN and the care they can offer you.
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Sources we used to develop this information
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Page last reviewed: 31 December 2025
Updated January 2026
Next review due: 31 December 2028
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